رحاب صبحي رمضان
  • Study of anti- inflammatory effect of Tribulus terrestris extract on bacterial infected wounds in mice
  • The effect of water extract from Tribulus terrestris was studied as an antiinflammatory
    agent
    on
    albino
    mice
    with
    Staph
    aureus
    infected
    wounds
    and
    investigating

    the
    toxicity
    of
    this
    substance.
    Two
    groups
    with
    ten
    mice
    in
    each
    one
    were
    used
    to
    conclude

    this
    part.
    The
    first
    one
    served
    as
    control
    that
    was
    wounded
    and
    infected
    by
    Staphylococcus

    aureus 
    and
    left
    for
    normal
    healing
    ,
    while
    the
    other
    group
    was
    treated
    with
    the
    extract

    after

    wounds were contaminated and infected with Staphylococcus aureus. The results
    showed an accelerated healing in wounds treated with T. terrestris compared with control.
    The cytotoxicity was performed on three groups of mice; every group included ten mice
    divided as: control group, the second group was orally administrated with 75mg/kg of the
    aqueous extract; the third group was administrated orally with 25mg/kg of the aqueous
    extract. The administration last for 10 days. After 10 days, mice were killed and put for
    autopsy histology slides were made from kidney and liver and compared with control
    group. No change was observed among studied slides which may indicate that the extract
    has no toxic effect on organs.